It might be a mistake, but like you I don't think the fact that 5.1 does not define EU as including UK was a drafting error. Quite the opposite, hence the the very explicit wording of 5.4 designed to remove doubt.
I expect AZ's lawyers, especially if they are the ones who worked on the agreement, are telling them they are fireproof. The best reasonable endeavours (what a mish mash) wording can only have been agreed to because it got AZ off the hook off a contractual obligation to supply.
If reasonable endeavours means they have to try, then best reasonable endeavours can only mean they have to really try. How is 'trying' not 'really trying'? They are the same, unless you have to rank one against the other.
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